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Semaglutide CAS 910463-68-2

24/ديسمبر/2024 08:23   خدمات   Bilqās   3 الآراء المرجعي: 48162

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موقعك: Bilqās

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Aglutide is a long-acting glucagon like peptide-1 (GLP-1) receptor agonist, mainly used to treat type 2 diabetes and obesity.
Chemical characteristics and mechanism of action
Semaglutide is a long-acting analogue of human glucagon like peptide-1 (GLP-1), with 94% of the human GLP-1 sequence. It has a high GLP-1 receptor affinity (0.38 0.06 nM) by substitution of two amino acids and derivatization at lysine 26. Semaglutide reduces blood sugar by stimulating insulin release, while inhibiting glucagon secretion, delaying gastric emptying, and reducing food intake through central appetite suppression, thereby achieving the effect of lowering blood sugar and weight

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